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Colesevelam Hydrochloride

CAS No. 182815-44-7

Colesevelam Hydrochloride ( —— )

Catalog No. M28036 CAS No. 182815-44-7

Colesevelam Hydrochloride is a bile acid sequestrant with a higher affinity for glycocholic acid in vitro. Colesevelam Hydrochloride inhibits bile acid reabsorption, leading to increased bile acid synthesis and reduces cholesterol levels in patients.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Colesevelam Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Colesevelam Hydrochloride is a bile acid sequestrant with a higher affinity for glycocholic acid in vitro. Colesevelam Hydrochloride inhibits bile acid reabsorption, leading to increased bile acid synthesis and reduces cholesterol levels in patients.
  • Description
    Colesevelam Hydrochloride is a bile acid sequestrant with a higher affinity for glycocholic acid in vitro. Colesevelam Hydrochloride inhibits bile acid reabsorption, leading to increased bile acid synthesis and reduces cholesterol levels in patients.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antioxidant;ERK;(HO)-1;IL Receptor;JNK;MAPK;NF-κB;PGE;TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    182815-44-7
  • Formula Weight
    618.3
  • Molecular Formula
    C31H67Cl3N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.[Cl-].NCC=C.ClCC1CO1.CCCCCCCCCCNCC=C.C[N+](C)(C)CCCCCCNCC=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li B, et al. Involvement of heme oxygenase-1 induction in the cytoprotective and immunomodulatory activities of 6,4'-dihydroxy-7-methoxyflavanone in murine hippocampal and microglia cells. Eur J Pharmacol. 2012 Jan 15;674(2-3):153-62.
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